Publications

Jun - Sep 2023

Nancy Y IP, LIFS

Melanocortin receptor activation alleviates amyloid pathology and glial reactivity in an Alzheimer's disease transgenic mouse model

Lau, Ka Yan Jackie; Tian, Min; Shen, Yang; Lau, Shun Fat; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu. Melanocortin receptor activation alleviates amyloid pathology and glial reactivity in an Alzheimer’s disease transgenic mouse model. Scientific Reports, v. 11, (1), February 2021, article number 4359

Equipment:

Equipment's name

Nancy Y IP, LIFS

Large-scale plasma proteomic profiling identifies a high-performance biomarker panel for Alzheimer's disease screening and staging

Jiang, Yuanbing; Zhou, Xiaopu; Ip, Fanny Chui Fun; Chan, Philip; Chen, Yu; Lai, Nicole C. H.; Cheung, Kit; Lo, Ronnie M. N.; Tong, Pui Sze; Wong, Bonnie W. Y.; Chan, Andrew L. T.; Mok, Vincent C. T.; Kwok, Timothy C. Y.; Mok, Kin Ying Boniface; Hardy, John; Zetterberg, Henrik; Fu, Kit Yu; Ip, Nancy Yuk-yu. Large-scale plasma proteomic profiling identifies a high-performance biomarker panel for Alzheimer's disease screening and staging. Alzheimer's and Dementia, 25 May 2021

Equipment:

Equipment's name

Nancy Y IP, LIFS

Instructive roles of astrocytes in hippocampal synaptic plasticity: neuronal activity-dependent regulatory mechanisms

Wang, Ye; Fu, Kit Yu; Ip, Nancy Yuk-yu. Instructive roles of astrocytes in hippocampal synaptic plasticity: neuronal activity-dependent regulatory mechanisms. FEBS Journal, 10 May 2021

Equipment:

Equipment's name

Nancy Y IP, LIFS

High-resolution two-photon transcranial imaging of brain using direct wavefront sensing

Chen, Congping; Qin, Zhongya; He, Sicong; Liu, Shaojun; Lau, Shun Fat; Wu, Wanjie; Zhu, Dan; Ip, Nancy Yuk-yu; Qu, Jianan. High-resolution two-photon transcranial imaging of brain using direct wavefront sensing. Photonics Research, v. 9, (6), June 2021, p. 1144-1156

Equipment:

Equipment's name

Nancy Y IP, LIFS

Efficient manipulation of gene dosage in human iPSCs using CRISPR/Cas9 nickases

Ye, Tao; Duan, Yangyang; Tsang, Hayley Wing Sum; Xu, He; Chen, Yuewen; Cao, Han; Chen, Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu. Efficient manipulation of gene dosage in human iPSCs using CRISPR/Cas9 nickases. Communications Biology, v. 4, (1), February 2021, article number 195

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Equipment's name

Dec 2023

Karl W K TSIM

Regulation of acetylcholinesterase during the lipopolysaccharide-induced inflammatory responses in microglial cells

Xia, Yingjie; Wu, Qiyun; Mak, Shing Hung; Liu, Yunle; Zheng, Zhongyu; Dong, Ting Xia Tina; Pi, Rongbiao; Tsim, Karl Wah Keung. Regulation of Acetylcholinesterase during the lipopolysaccharide-induced inflammatory responses in microglial cells. FASEB Journal, v. 36, (3), March 2022, article number e22189

Equipment:

Equipment's name

Karl W K TSIM

Capsaicin, a Phytochemical From Chili Pepper, Alleviates the Ultraviolet Irradiation-Induced Decline of Collagen in Dermal Fibroblast via Blocking the Generation of Reactive Oxygen Species

Wu, Qiyun; Bai, Panzhu; Guo, Hongsheng; Guo, Suisui; Xia, Yingjie; Xia, Yiteng; Gao, Xiong; Wang, Xiaoyang; Wu, Jiahui; Dong, Tingxia; Tsim, Karl Wah Keung. Capsaicin, a phytochemical from chili pepper, alleviates the ultraviolet irradiation-induced decline of collagen in dermal fibroblast via blocking the generation of reactive oxygen species. Frontiers in Pharmacology, v. 13, March 2022, article number 872912

Equipment:

Equipment's name

Karl W K TSIM

Scutellarin potentiates the skin regenerative function of self growth colony, an optimized platelet-rich plasma extract, in cultured keratinocytes through VEGF receptor and MAPK signaling

Guo, Suisui Maggie; Gao, Xiong; Hu, Weihui; Wang, Xioayang; Dong, Ting Xia; Tsim, Karl Wah Keung. Scutellarin potentiates the skin regenerative function of self growth colony, an optimized platelet-rich plasma extract, in cultured keratinocytes through VEGF receptor and MAPK signaling. Journal of Cosmetic Dermatology, 26 January 2022, article number 14800

Equipment:

Equipment's name

Karl W K TSIM

Tectoridin Stimulates the Activity of Human Dermal Papilla Cells and Promotes Hair Shaft Elongation in Mouse Vibrissae Hair Follicle Culture

Yuen, Ka Wing Gary; Ho, Bryan Siu-yin; Lin, Shengying Lish; Dong, Ting Xia Tina; Tsim, KarlWah Keung. Tectoridin stimulates the activity of human dermal papilla cells and promotes hair shaft elongation in mouse vibrissae hair follicle culture. Molecules, v. 27, (2), January 2022, article number 400

Equipment:

Equipment's name

Kai LIU, LIFS

Long-term in vivo imaging of mouse spinal cord through an optically cleared intervertebral window

Wu, Wanjie; He, Sicong; Wu, Junqiang; Chen, Conping; Li, Xuesong; Liu, Kai; Qu, Jianan Y.Long-term in vivo imaging of mouse spinal cord through an optically cleared intervertebral window. Nature Communications, v. 13, (1), April 2022, article number 1959

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Equipment's name

Jun - Sep 2023

Karl W K TSIM, LIFS

Quantitative analysis of fermented aerial part of Bupleurum chinense and prediction of their antimicrobial activity

郭舒臣; 郭瑞; 夏翊腾; 董婷霞; 王怀友; 詹华强发酵柴胡地上部分定量分析及其抗菌活性成分预测Quantitative analysis of fermented aerial part of Bupleurum chinense and prediction of their antimicrobial activity. 中国中药杂志=China Journal of Chinese Materia Medica, v. 45, (17), September 2020, p. 4238-4245

Equipment:

Equipment's name

Karl W K TSIM, LIFS

The herbal extract deriving from aerial parts of Scutellaria baicalensis shows anti-inflammation and anti-hypoxia responses in cultured fin cells from rabbit fish

Xia, Yiteng; Hu, Weihui; Wu, Qiyun; Dong, Tingxia Tina; Duan, Ran; Xiao, Jian; Li, Shaoping; Wang, Wenxiong; Qin, Qiwei; Tsim, Karl Wah Keung. The Herbal Extract Deriving From Aerial Parts of Scutellaria Baicalensis Shows Anti-inflammation and Anti-hypoxia Responses in Cultured Fin Cells From Rabbit Fish. Fish & Shellfish Immunology, v. 106, November 2020, p. 71-78

Equipment:

Equipment's name

Karl W K TSIM, LIFS

The Cholinesterase Inhibitory Properties of Stephaniae Tetrandrae Radix

Kong, Xiangpeng; Ren, Haiqin; Liu, Yunle; Leung, Ka Wing; Guo, Shuchen; Duan, Ran; Dong, Ting Xia; Tsim, Karl Wah Keung. The Cholinesterase Inhibitory Properties of Stephaniae Tetrandrae Radix. Molecules, v. 25, (24), December 2020, article number 5914

Equipment:

Equipment's name

Karl W K TSIM, LIFS

The Chinese medicinal herbs of spleen-meridian property regulate body temperature in yeast-induced fever rats

Huang, Yun; Yao, Ping; Leung, Ka Wing; Wang, Huaiyou; Kong, Xiangpeng; Dong, Ting Xia; Chen, Yicun; Qin, Qiwei; Tsim, Karl Wah Keung. The Chinese Medicinal Herbs of Spleen-meridian Property Regulate Body Temperature in Yeast-induced Fever Rats. Phytomedicine, v. 74, August 2020, article number 152815

Equipment:

Equipment's name

Karl W K TSIM, LIFS

The anti-bacterial effects of aerial parts of Scutellaria baicalensis: Potential application as an additive in aquaculture feedings

Xia, Yiteng; Chan, Kar Lun Gallant; Wang, Huaiyou; Dong, Tingxia; Duan, Ran; Hu, Weihui; Qin, Qi-Wei; Wang, Wenxiong; Tsim, Karl Wah Keung. The anti-bacterial effects of aerial parts of Scutellaria baicalensis: Potential application as an additive in aquaculture feedings. Aquaculture, v. 526, September 2020, article number 735418

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Our Team

Publications

Jun - Sep 2023

Melanocortin receptor activation alleviates amyloid pathology and glial reactivity in an Alzheimer's disease transgenic mouse model

Large-scale plasma proteomic profiling identifies a high-performance biomarker panel for Alzheimer's disease screening and staging

Instructive roles of astrocytes in hippocampal synaptic plasticity: neuronal activity-dependent regulatory mechanisms

High-resolution two-photon transcranial imaging of brain using direct wavefront sensing

Efficient manipulation of gene dosage in human iPSCs using CRISPR/Cas9 nickases

Title

Dec 2023

Regulation of acetylcholinesterase during the lipopolysaccharide-induced inflammatory responses in microglial cells

Capsaicin, a Phytochemical From Chili Pepper, Alleviates the Ultraviolet Irradiation-Induced Decline of Collagen in Dermal Fibroblast via Blocking the Generation of Reactive Oxygen Species

Scutellarin potentiates the skin regenerative function of self growth colony, an optimized platelet-rich plasma extract, in cultured keratinocytes through VEGF receptor and MAPK signaling

Tectoridin Stimulates the Activity of Human Dermal Papilla Cells and Promotes Hair Shaft Elongation in Mouse Vibrissae Hair Follicle Culture

Long-term in vivo imaging of mouse spinal cord through an optically cleared intervertebral window

Jun - Sep 2023

Quantitative analysis of fermented aerial part of Bupleurum chinense and prediction of their antimicrobial activity

The herbal extract deriving from aerial parts of Scutellaria baicalensis shows anti-inflammation and anti-hypoxia responses in cultured fin cells from rabbit fish

The Cholinesterase Inhibitory Properties of Stephaniae Tetrandrae Radix

The Chinese medicinal herbs of spleen-meridian property regulate body temperature in yeast-induced fever rats

The anti-bacterial effects of aerial parts of Scutellaria baicalensis: Potential application as an additive in aquaculture feedings